Patent Portfolio

Awarded Patents

Bioactive/Antimicrobial, Non-Disposable Personal Protection Equipment that Safely Kills Viral, Bacterial, and Fungal Matter Upon Contact. 

Patent # 10,934,168

Issued Mar. 3, 2021

Abstract: The present invention relates to a bioactive or real-time and pathogen killing material comprised of a carbon nanostructure (preferably a fullerene but including other functionalized carbon-based nanostructures) that possess potent broad-spectrum antimicrobial properties. The present invention relates to the utilization of functionalized carbon nanostructures as a bioactive antimicrobial substance that is incorporated into a material, including a textile, fabric, solution, salve, or cream. The preferred embodiment of the present invention is fullerene derivatives that are chemically functionalized on the cage with a halogen element. The present invention pertains to a material that is suitable for barrier garments, accessory garments (shoe covers, masks, facial visors, etc.), textiles (bed sheets, blankets, towels, personal clothing, gowns, surgical drapes, curtains, drapes, pads, etc.), filtration matrices (for use in hemodialysis, hemofiltration, etc.), or aerosolized solutions, sprays, liquids, salves, or creams. The present invention further relates to a production method thereof.

Self-Contained, Mobile Breathing Apparatus or Appliance that Supplies Pathogen and Endotoxin Free, Rhythmically Breathable Air to the Wearer or Treated Space through Active, Continuous Bio-Deactivation and Destruction of Bacteria, Fungi, Viral and Allergenic/Antigenic Matter Safely when Using Benign, Household, Rechargeable Filtration Media.

Patent # 11,219,255

Issued Jan. 11, 2022

Abstract: The present invention relates to a protective face mask and filtration article, a method for using a protective face mask and filtration article, and a design for manufacturing. In particular, the invention relates to a self-contained, mobile, battery-powered bioactive and filtering breathing appliance that provides broad spectrum antimicrobial and allergic protection via an atomized biocidal agent steam/vapor and a torturous hydrophilic filtration article that sterilizes incoming air and captures debris. To this end, antimicrobial activity and filtration functions leverage a redundancy of means/methods comprised of antimicrobial hydrogen peroxide liquid/vapor/steam and an iodized salt containing hydrophilic filtration article. The present invention is a wearable apparatus that sterilizes incoming air by capturing, neutralizing and destroying airborne pathogens and other particulate matter and pumps sterilized oxygen/air for natural, unlabored breathing by the wearer. The present invention further relates to a production method thereof.

Halogenated Fullerene Functionalized as a Biocidal and Chemotactic Spermicide to Vaginally Harbor and Neutralize Spermatozoa for Use as a Safe and Effective Contraceptive.

Patent # 11,298,375

Issued Apr. 12, 2022

Abstract: The present invention provides the methods and composition useful as a contraceptive by preventing motile sperm from reaching a mature ovum, thereby blocking fertilization and preventing pregnancy. The contraceptive is comprised of halogen functionalized fullerene nanoparticles (halo fullerenes) and chemotactic stimulants that act synergistically to divert, incapacitate and ultimately rupture spermatozoa to avert fertilization. When applied vaginally prior to coitus, the suspension is activated by exposure to spermatozoa upon insemination. Notably, non-spermatozoa cells are unaffected by the pH-neutral suspension; however, closer to the same scale, microbes are susceptible to its inherent biocidal properties. Following application and coitus, the contraceptive evacuates naturally, along with seminal and vaginal fluids thereafter.

Innocuous Sterilant using Hemocyanin and Functionalized Fullerenes with Broad-Spectrum Intracellular and Interstitial Microbiocidal and Radical Scavenging Effects for Packaged Matter, Biologics and Organics including Liquids, Gases, Tissue, Organs, Cells, and Limbs with Copper Mediated Oxygenation for Viability and Preservation

Patent # TBD

Awarded Aug. 8, 2022

Abstract: Tissue and organ transplantation success is chiefly dependent on the harvest and preservation techniques employed. Yield and quality enhancements are needed, because qualified patient demand far outpaces donors and ultimately, tissues and organs stored and transported so as to render them in acceptable condition for surgery. In the case of corneal transplants, tissue supplies help 1 out of 70 patients in need despite being among the most successful such procedures today. Transplant success has improved overall with enhanced storage and transport methods that have allowed for greater time and distances to reach patients in need, whether corneas, kidneys, hearts, lungs, livers or other tissues, limbs or cellular materials. While corneal tissues specifically benefit from oxygenation via direct air contact and normal tears in a healthy individual, once donated, the lack of corneal vascularization can uniquely accelerate the depletion of oxygen that occurs upon harvesting of all transplant materials. Directly infusing oxygen has had little impact, given partial pressure requirements, volatility and reactivity to many compounds, including self-affinity or agglomeration and bubbling. However, the hemocyanin, such as that of the horseshoe crab (Limulus polyphemus), can deliver oxygen directly to transplant tissues, while free radical scavenging by pristine fullerenes can help maintain cellular integrity. Horseshoe crabs have successfully evolved by developing two immunological mechanisms, amoebocytes and less characterized antiviral and gram-positive bactericidal properties ascribed to other hemolymph constituents. The amoebocytes have a specific, ultra sensitive affinity to gram negative bacteria and fungi; they engulf and consume these microbes in an enzymatic coagulation process. However, hemocyanin is extracellular and non-toxic to mammalian tissue, notwithstanding its microbiocidal properties. As such, the viral-scale peptides appear to intracellularly invade the pathogens and disrupt replication without conferring a caustic or toxic effect on non-pathogenic tissue. Hence, hemocyanin appears to be non-immunogenic and thus applicable as a carrier molecule for some human therapeutics (e.g., hemocyanin from Keyhole Limpet snails). The present invention relates in the initial embodiment to the use of horseshoe crab hemocyanin and functionalized carbon nanostructures, halogenated fullerenes, pristine fullerenes and fullerene derivatives as an antimicrobial and antioxidant enrichment composition that is added to tissue storage and preservation media as a potent, broad-spectrum antimicrobial and tissue preservation composition for safe and effective storage and transport. Notably, methods for horseshoe crab aquaculture husbandry have been developed to achieve sustainable hemocyanin supplies for hemolymph harvest and biomedical applications. With regard to unique needs and benefits for the transplantation of corneal tissue, the aim of this patent is development of an antioxidant and broad-spectrum microbicidal that is benign to endothelial and endothelium cells to preserve and maximize the viability of a pathogen-free specimen.

Pending Patents

Unassisted Robotic Surgery Employing Paramagnetic Halo Metallofullerenes as Minimally Invasive, Precision Scalpels or Micronization Particles through Magnetic Field Manipulation and Targeted Exenteration Patterned by Programmed 3D Imaging Using Needle or Magnetic Energy Access and Microelectronic Semiconducting in Non-stationary Wafer-less Space.

Patent Application # 17/884,185

Filed Aug. 9, 2022 – In Review

Abstract: Pending

Practical Infectious Disease Prevention and Mitigation Chemistry for Skin Contact Infections and especially Sexual (STIs) via Disruption of Skin Surface Microbes using Surface Barrier and Atomic Scale, Biocidal Fullerene Particles and Volatile Water-based Reaction Chemistries that Cleanse the Skin Surface and Reduce Pathogenic Matter and Subsequent Malady, Morbidity and Mortality in Multiple Formulations and Delivery Mechanisms 

Provisional Application # 63/397,950

Filed Aug. 15, 2022

Abstract: Pending